Your profile is always live. What does this mean? It means that as soon as you make an update to it any employer who has access to it will see that update.
Got some new experience? Changed what location you are living in?, Picked up some new skills?, Have different availability you can work?
As soon as you update your profile with this new information, the employer will see it. It might have been that they ruled you out for a role as you were in the wrong location, weren't available for the times they were looking for staff and so on.
Keeping your profile up to date is the best way of giving yourself the best opportunity to find the role you are looking for.